Sexual Health & Low Testosterone
Evidence-graded supplements studied for erectile function, libido, and testosterone in men. Grades reflect the strength of the human trial evidence for each specific use, most of this area rests on small or short trials.
At a glance
The letters on this page
Six interventions on this page. Three carry a letter; three are listed without one, with the reason.
How it is measured
What has been graded
Not graded for this use. Ashwagandha's graded uses are stress, anxiety and sleep, not erectile function, libido or testosterone.
Graded for correcting a deficiency, not for raising testosterone in men with normal zinc
Not graded for this use. Zinc is graded for common-cold duration in adults. Correcting a deficiency is not a graded use, and no cited trial tested testosterone in men with normal zinc.
Not graded for this use. L-citrulline is graded on blood pressure (C) and on exercise performance (D). No trial on this record measured erectile function, so this row carries no letter.
Cautions
- •PDE5 inhibitors (sildenafil, tadalafil) are the evidence-based first-line medical therapy for ED; discuss with a clinician.
- •Testosterone replacement therapy is a prescription decision requiring lab confirmation of deficiency.
Anything in this page is educational only. Whether to start, stop or change a supplement for this condition, and how it fits with any medication you take, is a decision for your clinician. The Drug-Nutrient Depletion tool and the Contraindications Search are designed to help you prepare that conversation.
Disclosure
These statements have not been evaluated by the Food and Drug Administration. Any grade on this page describes the strength of published human trial evidence in the populations studied. It is not a recommendation for any individual and is not medical advice. Starting, stopping or changing any supplement or medication is a decision for your physician.