Drug Nutrient Depletion Checker
Find out exactly which nutrients your prescription medications are depleting — and what to do about it. Enter your medications and get a ranked list of deficiencies, repletion protocols, and interaction flags.
Built by a clinician with 47 years in nutrition and longevity. Designed for people who want real answers — not marketing copy.
Follow the sequence or jump to the step that fits where you are right now.
Other sites charge $180 a year to access the same kind of research translation you’re reading right now. We think that’s backwards. Evidence-based health information should be accessible to anyone who wants it — not just subscribers.
This site is funded by commission relationships with brands whose products already passed our evidence review. Those relationships are disclosed on every product page. The commissions never influence ratings — evidence gates come first, commercial relationships follow.
Every intervention in science and medicine follows the same method: establish a baseline → apply the protocol → measure the result. Biological age testing is how you apply that principle to your own body. Without a before, there is no after. Without data, you're hoping.
By the time most people start paying attention, a decade of peak biological function is already behind them. Undiagnosed metabolic shifts, chronic low-grade inflammation, and cellular decline move silently — years before any symptom appears. The evidence is clear: early, data-driven intervention changes the trajectory. Late intervention manages the damage.
The best time to start was ten years ago. The second best time is today.
Start My Longevity Checkup →Find out exactly which nutrients your prescription medications are depleting — and what to do about it. Enter your medications and get a ranked list of deficiencies, repletion protocols, and interaction flags.
Paste your lab values and get a longevity-optimized interpretation — not just "normal range," but optimal range based on published trial thresholds. Understand where you stand on the biomarkers that actually matter.
Understanding your labs is step one. Step two is knowing which evidence-backed interventions address what you found.
Side-by-side comparison of the top longevity supplements by form, dose, bioavailability, and clinical evidence tier. Cut through the noise and see which products are worth your money.
After comparing, save your results or email them to yourself for future reference.
Find out how old your body actually is — not just how old the calendar says you are. Enter your epigenetic test result from TruDiagnostic or any clock-based test, or answer 8 lifestyle questions for an estimate. Results shown on a real-time visual score dial.
The single most powerful predictor of how long you will live. Enter your VO2 Max from a wearable device, a Cooper run test, or a lab measurement. We score it against age-sex norms and show your longevity percentile on a visual score dial.
Build a personalized longevity supplement stack based on your health goals, budget, and current medications. Each recommendation links to the evidence tier that earned it a place in your protocol.
Check for known interactions between supplements and medications. Flags synergistic pairs, competitive absorption issues, and timing conflicts — all grounded in published pharmacokinetic data.
Estimate your biological age using validated proxies from published longevity research. Inputs include grip strength, resting heart rate, VO2 max, sleep quality, and key biomarkers. Outputs a composite score with modifiable factors ranked by impact.
Track your supplement protocol and log how you feel week over week. Compare your self-reported outcomes to the expected effects described in human trial data — so you can separate placebo from real response.
Answer a few targeted questions about your age, risk factors, symptoms, and current medications. Get a prioritized, evidence-ranked testing roadmap — so you start with the diagnostics that matter most for your profile.
Set a reminder to retest in 90 days — that is the minimum window to detect meaningful change in most biomarkers.
Score your heart health across 8 evidence-based factors — diet, physical activity, sleep, BMI, blood lipids, glucose, blood pressure, and nicotine. See exactly which factors move the needle most for longevity.
The average American scores 65/100 — a D+ on any grading scale. See where you stand and which single factor would help you most.
See what the clinical trials actually showed about your prescription — absolute risk, Number Needed to Treat (NNT), which nutrients your medication depletes, and what the evidence says about nutritional support. No hype. Just the numbers.
20 questions. Find out which of 6 longevity phenotype clusters fits your biology — Mitochondrial Optimizer, Inflammaging Profile, Metabolic Edge, Cognitive Reserve, Hormonal Architect, or Cellular Renewal — and get a personalized starting path.
The inverse resource the supplement industry never built. Search any supplement and see who should avoid it or use caution — by health condition, medication class, or genetic variant. Safety before spend.
Is your supplement spend justified by the science? Enter a supplement and your monthly cost — get an evidence-weighted ROI score and cost-per-evidence-point. Most users find $40–80/month in optimization opportunities.
24 questions map your symptoms and patterns to the 12 Hallmarks of Aging framework (López-Otín et al. 2023). See which hallmarks are most active in your biology and which evidence-based interventions target each.
Timing changes the effect size of supplements more than most people realize. Enter your stack and schedule — get a personalized optimized daily plan with evidence-based timing for every supplement you take.
Are you unknowingly double-dosing nutrients across multiple products? Getting 500% of your B12 from three different formulas? This tool finds redundant mechanisms, overlapping nutrients, and potential mega-dose situations in your stack.
Enter your current biological age estimate and select your interventions. The simulator models how much each validated lifestyle change or supplement could shift your biological age over 12 months — based on published effect sizes from epigenetic clock studies.
Generate a structured clinical summary before the patient arrives. Enter medications, chief complaint, and goals — or paste a SOAP note — and get NNT context, nutrient depletion flags, suggested labs, and discussion points in under 60 seconds.
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